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2-Fluorophenylsulfonylethanol CAS NO 685892-16-4


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CAS No.:685892-16-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Fluorophenylsulfonylethanol is a specialized fluorinated sulfonyl building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine and sulfonyl groups can dramatically alter biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures. Its precise structure offers a versatile handle for further functionalization in medicinal chemistry campaigns.

Application

  • As a critical pharmaceutical intermediate in the synthesis of novel drug candidates, particularly kinase inhibitors and receptor modulators.
  • Utilized in agrochemical research for the development of new herbicides and fungicides with enhanced efficacy.
  • Serves as a versatile building block in organic synthesis for introducing fluorinated sulfonylethanol motifs.
  • Potential use in the development of functional materials, such as ligands for catalysis or monomers for specialty polymers.
  • Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
  • Acts as a precursor for the synthesis of more complex sulfone-based compounds used in various chemical applications.

Basic Information

Product Name 2-Fluorophenylsulfonylethanol
CAS No. 685892-16-4
Molecular Formula C8H9FO3S
Molecular Weight 204.22 g/mol
Synonyms 2-(2-Fluorophenylsulfonyl)ethanol; 1-(2-Fluorophenylsulfonyl)-2-ethanol; Ethanol, 2-[(2-fluorophenyl)sulfonyl]-; 2-Fluoro-benzenesulfonic acid 2-hydroxyethyl ester; α-Fluoro-ω-hydroxyphenyl sulfone; 2-Fluorobenzenesulfonylethanol; 2-Fluoro phenyl sulfone ethanol; 2-FPS-EtOH
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Quality Control

Our 2-Fluorophenylsulfonylethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment. We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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