Description

2,6-Difluoro-3,5-Diiodopyridine is a highly functionalized pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it a versatile intermediate for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and R&D teams in the life sciences sector who require precise, high-purity intermediates to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the fluorine and iodine substituents enhance biological activity and environmental stability.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for OLEDs and charge-transport materials, due to its electron-deficient pyridine core.
• Cross-Coupling Reactions: Serves as an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to introduce the diiodo functionality into complex architectures.
• Ligand and Catalyst Development: Utilized to synthesize novel nitrogen-based ligands for transition metal catalysts used in asymmetric synthesis and polymerization.
• Chemical Biology Probes: Acts as a scaffold for developing fluorescent probes or photoaffinity labels for studying biological systems and protein interactions.

Basic Information

Product Name	2,6-Difluoro-3,5-Diiodopyridine
CAS No.	685517-77-5
Molecular Formula	C5HF2I2N
Molecular Weight	398.87 g/mol
Synonyms	3,5-Diiodo-2,6-difluoropyridine; 2,6-Difluoro-3,5-diiodopyridine; Pyridine, 3,5-diiodo-2,6-difluoro-; 685517-77-5; 3,5-Diiodo-2,6-difluoropyridine; 2,6-Difluoro-3,5-diiodo-pyridine
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3,5-Diiodopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.