Description

Benzo[B]Thiophene-6-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound is essential for introducing the benzo[b]thiophene-6-sulfonyl moiety, a key functional group in the development of novel active pharmaceutical ingredients and specialty chemicals. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new molecular entities with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic structure.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the creation of activity-based probes and labeling reagents for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex organic molecules for clients.

Basic Information

Product Name	Benzo[B]Thiophene-6-Sulfonyl Chloride
CAS No.	685129-19-5
Molecular Formula	C8H5ClO2S2
Molecular Weight	232.71 g/mol
Synonyms	1-Benzothiophene-6-sulfonyl chloride; 6-Thianaphthenesulfonyl chloride; Benzo[b]thiophene-6-sulfonyl chloride; 6-Benzo[b]thienylsulfonyl chloride; BT-6-SO2Cl; 685129-19-5 (CAS); 1-Benzothiophene-6-sulfonoyl chloride
EINECS	Contact for details

Quality Control

Our Benzo[B]Thiophene-6-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.