Description

Cyclopropane, 1-Bromo-2-Fluoro-3-Methyl-, (1R,2R,3S)-Rel- (9Ci) is a high-value, stereochemically defined cyclopropane derivative, serving as a critical chiral building block in advanced organic synthesis. Its precise stereochemistry and unique halogenated structure make it indispensable for constructing complex molecular architectures with high enantiomeric purity. This compound is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and CNS-targeted drug candidates.
• Agrochemical Synthesis: Used in the synthesis of advanced, stereoselective pesticides and herbicides where the specific spatial arrangement of atoms is crucial for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to control reaction stereochemistry.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized as a molecular scaffold for creating probes that study enzyme mechanisms and protein-ligand interactions.

Basic Information

Product Name	Cyclopropane, 1-Bromo-2-Fluoro-3-Methyl-, (1R,2R,3S)-Rel- (9Ci)
CAS No.	681536-89-0
Molecular Formula	C4H6BrF
Molecular Weight	153.00 g/mol
Synonyms	(1R,2R,3S)-1-Bromo-2-fluoro-3-methylcyclopropane; rel-(1R,2R,3S)-1-Bromo-2-fluoro-3-methylcyclopropane; 1-Bromo-2-fluoro-3-methylcyclopropane, (1R,2R,3S)-rel-; 681536-89-0; Cyclopropane, 1-bromo-2-fluoro-3-methyl-, (1R,2R,3S)-rel-; (1R,2R,3S)-rel-1-Bromo-2-fluoro-3-methylcyclopropane; Bromofluoromethylcyclopropane stereoisomer
EINECS	Contact for details

Quality Control

Our production of Cyclopropane, 1-Bromo-2-Fluoro-3-Methyl-, (1R,2R,3S)-Rel- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity, critical for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC-MS, and NMR spectroscopy. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment. Our quality management system supports compliance with cGMP and ISO standards for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and purity. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.