Description

Ethyl 4-Fluoro-5-Methyl-1H-Pyrazole-3-Carboxylate is a high-value fluorinated pyrazole derivative, a crucial building block in modern synthetic organic chemistry. Its molecular structure, featuring both fluorine and an ester group, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Serves as a core building block for creating advanced pesticides, herbicides, and fungicides with improved efficacy and environmental profiles.
• Material Science Research: Used in the development of specialty chemicals, advanced polymers, and functional materials that require fluorinated heterocyclic components.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs serving the life sciences sector.

Basic Information

Product Name	Ethyl 4-Fluoro-5-Methyl-1H-Pyrazole-3-Carboxylate
CAS No.	681034-80-0
Molecular Formula	C7H9FN2O2
Molecular Weight	172.16 g/mol
Synonyms	Ethyl 4-Fluoro-5-methyl-1H-pyrazole-3-carboxylate; 4-Fluoro-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester; 1H-Pyrazole-3-carboxylic acid, 4-fluoro-5-methyl-, ethyl ester; Ethyl 4-fluoro-5-methylpyrazole-3-carboxylate; 681034-80-0; 4-Fluoro-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Fluoro-5-Methyl-1H-Pyrazole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates for research and GMP starting material synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.