Description

5-Acetylamino-2-Ethoxy-Benzenesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional dyes. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for sulfonamide and sulfonate formation.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the sulfonyl moiety imparts specific biological activity.
• Dye and Pigment Manufacturing: Serves as a key component in the production of specialized azo dyes and pigments, contributing to color fastness and molecular stability.
• Functional Material Research: Employed in creating advanced polymers and materials with specific sulfonated properties for membranes or conductive applications.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic pathways and compound libraries.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule production.

Basic Information

Item	Detail
Product Name	5-Acetylamino-2-Ethoxy-Benzenesulfonyl Chloride
CAS No.	680618-19-3
Molecular Formula	C10H12ClNO4S
Molecular Weight	277.73 g/mol
Synonyms	5-Acetamido-2-ethoxybenzenesulfonyl chloride; N-[5-(Chlorosulfonyl)-2-ethoxyphenyl]acetamide; 2-Ethoxy-5-acetamidobenzenesulfonyl chloride; 5-Acetylamino-2-ethoxybenzenesulfonyl chloride; AEBS-Cl (common abbreviation); 2-Ethoxy-5-acetylaminobenzenesulfonyl chloride; 1-Acetyl-5-(chlorosulfonyl)-2-ethoxy-1H-benzenamine
EINECS	Contact for details

Quality Control

Every batch of 5-Acetylamino-2-Ethoxy-Benzenesulfonyl Chloride is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.