Description

2-Ethoxy-5-[(Pyrrolidine-1-Carbonyl)-Amino]-Benzenesulfonyl Chloride is a high-value sulfonyl chloride derivative and a key synthetic intermediate in advanced organic chemistry. This compound matters for its role as a versatile building block in the development of complex molecules, particularly in pharmaceutical research and fine chemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel sulfonamide-based structures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition via sulfonamide pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the benzenesulfonyl moiety is integral to biological activity.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling or modifying proteins and other biomolecules due to its sulfonyl chloride group.
• Material Science: Employed in the synthesis of specialized polymers and advanced materials requiring specific sulfonamide linkages.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for CROs and CDMOs producing bespoke compounds for client research programs.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical reactions.

Basic Information

Product Name	2-Ethoxy-5-[(Pyrrolidine-1-Carbonyl)-Amino]-Benzenesulfonyl Chloride
CAS No.	680618-12-6
Molecular Formula	C13H17ClN2O4S
Molecular Weight	332.80 g/mol
Synonyms	5-[(Pyrrolidine-1-carbonyl)amino]-2-ethoxybenzenesulfonyl chloride; 2-Ethoxy-5-[(pyrrolidine-1-carbonyl)amino]benzenesulfonyl chloride; N-(4-Ethoxy-3-sulfonylchloridophenyl)pyrrolidin-1-carboxamide; 1-(4-Ethoxy-3-sulfonylchloridophenylcarbamoyl)pyrrolidine; 680618-12-6; Benzenesulfonyl chloride, 2-ethoxy-5-[(1-pyrrolidinylcarbonyl)amino]-; Sulfonyl chloride intermediate 680618-12-6
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific batch results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.