Description

2-Ethoxy-5-[(Pyridine-3-Carbonyl)-Amino]-Benzenesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in modern organic synthesis. Its molecular structure, featuring both a sulfonyl chloride group and a pyridine-carbonyl-amino moiety, makes it a versatile building block for constructing complex molecules with high precision. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the sulfonamide linkage is a common pharmacophore.
• Dye and Pigment Synthesis: Serves as a key reactant for introducing sulfonamide groups into chromophore structures, modifying solubility and color properties.
• Material Science: Employed in the creation of specialty polymers and functional materials that require specific sulfonamide-based linkages for enhanced performance.
• Chemical Biology Probes: Utilized to create affinity labels or activity-based probes for studying biological pathways and protein function.

Basic Information

Product Name	2-Ethoxy-5-[(Pyridine-3-Carbonyl)-Amino]-Benzenesulfonyl Chloride
CAS No.	680618-09-1
Molecular Formula	C15H15ClN2O4S
Molecular Weight	354.81 g/mol
Synonyms	5-[(3-Pyridinylcarbonyl)amino]-2-ethoxybenzenesulfonyl chloride; N-(3-Ethoxy-4-sulfonylchlorophenyl)nicotinamide; 2-Ethoxy-5-(nicotinamido)benzenesulfonyl chloride; 680618-09-1; Benzenesulfonyl chloride, 2-ethoxy-5-[(3-pyridinecarbonyl)amino]-; Nicotinamide, N-[3-ethoxy-4-(chlorosulfonyl)phenyl]-
EINECS	Contact for details

Quality Control

Our production of 2-Ethoxy-5-[(Pyridine-3-Carbonyl)-Amino]-Benzenesulfonyl Chloride adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.