Description

2-Ethoxy-5-(Terephthalamido) Benzene-1-Sulfonyl Chloride is a high-purity, specialized organic intermediate featuring a reactive sulfonyl chloride group and a terephthalamido moiety. This compound is critical for the synthesis of advanced materials and fine chemicals where precise molecular architecture is required. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecules and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring sulfonamide or sulfonylurea linkages.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Polymer Modification: Serves as a functional monomer or cross-linking agent for creating high-performance polymers, such as polyamides and polyimides, with specific thermal or chemical resistance properties.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized azo dyes and organic pigments.
• Material Science Research: Employed in the development of advanced materials, including liquid crystals, organic semiconductors, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in proteomics and diagnostic assay development due to its reactive sulfonyl chloride group.

Basic Information

Product Name	2-Ethoxy-5-(Terephthalamido) Benzene-1-Sulfonyl Chloride
CAS No.	680618-05-7
Molecular Formula	C17H17ClN2O5S
Molecular Weight	396.85 g/mol
Synonyms	5-(Terephthalamido)-2-ethoxybenzenesulfonyl chloride; 2-Ethoxy-5-[(4-carbamoylbenzoyl)amino]benzenesulfonyl chloride; 4-[(4-Ethoxy-3-sulfonylchloridophenyl)carbamoyl]benzamide; 680618-05-7; Benzenesulfonyl chloride, 2-ethoxy-5-[(4-carbamoylbenzoyl)amino]-; Terephthalamido ethoxy benzene sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Ethoxy-5-(Terephthalamido) Benzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and IR spectroscopy, to ensure compliance with stringent purity specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available for each lot upon request, supporting your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.