Description

2-Chloro-4-[(Pyrrolidine-1-Carbonyl)-Amino]-Benzenesulfonyl Chloride is a high-purity, multi-functional sulfonyl chloride derivative designed for advanced chemical synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a reactive handle for sulfonamide bond formation. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides that leverage the sulfonyl moiety for bioactivity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying protein function and biological pathways.
• Material Science: Acts as a monomer or cross-linking agent in the creation of specialized polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Item	Details
Product Name	2-Chloro-4-[(Pyrrolidine-1-Carbonyl)-Amino]-Benzenesulfonyl Chloride
CAS No.	680617-79-2
Molecular Formula	C11H12Cl2N2O3S
Molecular Weight	323.19 g/mol
Synonyms	2-Chloro-4-(pyrrolidine-1-carboxamido)benzenesulfonyl chloride; 4-Amino-2-chloro-N-(pyrrolidin-1-yl)benzenesulfonamide-1-carbonyl chloride; 680617-79-2; 2-Chloro-4-(1-pyrrolidinecarboxamido)benzenesulfonyl chloride; 2-Chloro-4-[(1-pyrrolidinylcarbonyl)amino]benzenesulfonyl chloride; Benzenesulfonyl chloride, 2-chloro-4-[(1-pyrrolidinylcarbonyl)amino]-; 2-Chloro-4-(pyrrolidine-1-carbonylamino)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-[(Pyrrolidine-1-Carbonyl)-Amino]-Benzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.