Description

2-Chloro-4-[(Piperidine-1-Carbonyl)-Amino]-Benzenesulfonyl Chloride is a specialized sulfonyl chloride derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional reactivity, featuring both a sulfonyl chloride and a protected amine group, makes it an invaluable intermediate for constructing complex molecules with high precision. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for creating sulfonamide-based molecules with targeted biological activity.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the sulfonyl chloride moiety is essential for activity.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Intermediate for the production of specialty polymers and functional materials requiring specific sulfonamide linkages.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Chloro-4-[(Piperidine-1-Carbonyl)-Amino]-Benzenesulfonyl Chloride
CAS No.	680617-78-1
Molecular Formula	C12H14Cl2N2O3S
Molecular Weight	337.22 g/mol
Synonyms	2-Chloro-4-(piperidine-1-carboxamido)benzenesulfonyl chloride; 4-Amino-2-chlorobenzenesulfonyl chloride, N-piperidylcarbonyl; 680617-78-1; 2-Chloro-4-[(1-piperidinylcarbonyl)amino]benzenesulfonyl chloride; Benzenesulfonyl chloride, 2-chloro-4-[(1-piperidinylcarbonyl)amino]-; 2-Chloro-4-(piperidine-1-carbonylamino)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-[(Piperidine-1-Carbonyl)-Amino]-Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.