Description

2-Chloro-4-[(Morpholine-4-Carbonyl)-Amino]-Benzenesulfonyl Chloride is a high-value sulfonyl chloride derivative and a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a reactive sulfonyl chloride group and a protected amine, makes it indispensable for constructing complex molecules with specific pharmacological or material properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides that require a sulfonyl chloride moiety for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of specialty polymers and functionalized surfaces.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function and protein labeling.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	2-Chloro-4-[(Morpholine-4-Carbonyl)-Amino]-Benzenesulfonyl Chloride
CAS No.	680617-77-0
Molecular Formula	C11H12Cl2N2O4S
Molecular Weight	339.19 g/mol
Synonyms	4-Amino-2-chlorobenzenesulfonyl chloride, N-(morpholinocarbonyl) derivative; 2-Chloro-4-[(morpholine-4-carbonyl)amino]benzenesulfonyl chloride; 4-(Morpholine-4-carbonylamino)-2-chlorobenzenesulfonyl chloride; N-(4-Chloro-2-sulfonylchloridophenyl)morpholin-4-carboxamide; Morpholine-4-carboxylic acid (4-chloro-2-sulfonylchloridophenyl)amide
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-[(Morpholine-4-Carbonyl)-Amino]-Benzenesulfonyl Chloride is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.