Description

5-[(Morpholine-4-Carbonyl)-Amino]-Naphthalene-1-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative designed for advanced chemical synthesis. This compound serves as a critical building block for introducing a functionalized naphthalene-sulfonamide moiety into target molecules, enabling the development of novel compounds with specific biological or material properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for creating sulfonamide-based enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or pesticides by acting as a linking group to confer specific activity and stability.
• Fluorescent Probe Synthesis: Serves as a starting material for constructing naphthalene-based fluorescent dyes and sensors for biochemical assays and diagnostic applications.
• Polymer & Material Science: Employed to functionalize polymers or surfaces, introducing sulfonamide groups to alter solubility, adhesion, or other material properties.
• Chemical Biology Tool Development: Utilized in creating activity-based probes or affinity labels for studying protein function and interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke chemical synthesis projects requiring this specific sulfonyl chloride functionality.

Basic Information

Product Name	5-[(Morpholine-4-Carbonyl)-Amino]-Naphthalene-1-Sulfonyl Chloride
CAS No.	680185-44-8
Molecular Formula	C15H15ClN2O4S
Molecular Weight	354.81 g/mol
Synonyms	5-(Morpholine-4-carboxamido)naphthalene-1-sulfonyl chloride; 1-Naphthalenesulfonyl chloride, 5-[(4-morpholinylcarbonyl)amino]-; N-(1-Sulfonylchloridonaphthalen-5-yl)morpholine-4-carboxamide; 5-(Morpholin-4-ylcarbonylamino)naphthalene-1-sulfonyl chloride; 5-[(Morpholine-4-carbonyl)amino]naphthalene-1-sulphonyl chloride; 680185-44-8; 5-Morpholinocarbonylamino-1-naphthalenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 5-[(Morpholine-4-Carbonyl)-Amino]-Naphthalene-1-Sulfonyl Chloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure consistency and reliability for your synthetic workflows. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.