Description

4-Benzyloxy-[7-13C]Benzyl Alcohol CAS NO 680182-18-7 is a stable isotope-labeled derivative of benzyloxybenzyl alcohol, where the carbon-13 (13C) label provides a non-radioactive tracer for advanced analytical and research applications. This compound is critical for ensuring accuracy and reliability in quantitative mass spectrometry and metabolic pathway studies. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug metabolism and pharmacokinetics (DMPK) research, biomarker discovery, and internal standard synthesis.

Application

• Internal Standard for LC-MS/MS: Serves as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for the accurate measurement of unlabeled benzyloxybenzyl alcohol or related metabolites in complex biological matrices.
• Drug Metabolism Studies (DMPK): Used as a tracer to elucidate metabolic pathways, identify metabolites, and study the pharmacokinetic profile of pharmaceutical compounds in preclinical and clinical research.
• Stable Isotope Labeling: Acts as a key synthetic intermediate or building block for the preparation of more complex 13C-labeled compounds for use in various research programs.
• Biomarker Research: Enables precise tracking and quantification in proteomic and metabolomic studies to discover and validate disease biomarkers.
• Analytical Method Development: Essential for developing and validating highly sensitive and specific analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).
• Organic Synthesis Research: Utilized in mechanistic studies and synthetic chemistry to trace reaction pathways and intermediates.

Basic Information

Item	Detail
Product Name	4-Benzyloxy-[7-13C]Benzyl Alcohol
CAS No.	680182-18-7
Molecular Formula	C14H1213CO2 *
Molecular Weight	~215.25 g/mol *
Synonyms	4-(Benzyloxy)-[7-13C]benzenemethanol; [7-13C]-4-(Phenylmethoxy)benzyl Alcohol; 1-(Benzyloxy)-4-([13C]hydroxymethyl)benzene; 13C-Labeled 4-Benzyloxybenzyl Alcohol; 4-(Benzyloxy)benzyl-7-13C Alcohol; Isotope-labeled Benzyloxybenzyl Alcohol; Benzyl 4-(hydroxymethyl-7-13C)phenyl Ether
EINECS	Contact for details

* The molecular weight is approximate and varies with the exact isotopic enrichment.

Quality Control

Every batch of 4-Benzyloxy-[7-13C]Benzyl Alcohol is produced and analyzed under strict quality systems to ensure identity, purity, and isotopic enrichment meet the exacting standards required for analytical research. We provide comprehensive Certificates of Analysis (COA) that detail critical parameters including isotopic purity (atom % 13C), chemical purity (by HPLC/NMR), and specific analytical data. Our quality commitment supports compliance with GMP/GLP principles for use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This compound is easily oxidized; for long-term storage, consider keeping the container under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % 13C)	≥ 99% at labeled position
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.