Description

2-[(2R,6S)-2,6-Dimethyl-1,4-oxazinan-4-yl]-5-fluorobenzenecarbaldehyde is a high-purity, chiral fluorinated aromatic aldehyde building block. This compound is of significant value for its role as a key synthetic intermediate in the development of complex, biologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, leveraging its fluorinated aromatic structure.
• Ligand Synthesis: Serves as a starting material for creating sophisticated chiral ligands used in asymmetric catalysis.
• Chemical Research: Employed in academic and industrial R&D for exploring new organic reactions and constructing complex molecular architectures.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	2-[(2R,6S)-2,6-Dimethyl-1,4-oxazinan-4-yl]-5-fluorobenzenecarbaldehyde
CAS No.	679839-17-9
Molecular Formula	C₁₃H₁₆FNO₂
Molecular Weight	237.27 g/mol
Synonyms	5-Fluoro-2-[(2R,6S)-2,6-dimethyl-1,4-oxazinan-4-yl]benzaldehyde; (2R,6S)-4-(5-Fluoro-2-formylphenyl)-2,6-dimethylmorpholine; 5-Fluoro-2-((2R,6S)-2,6-dimethylmorpholino)benzaldehyde; 679839-17-9; 2,6-Dimethyl-4-(5-fluoro-2-formylphenyl)morpholine (stereo); Fluorinated chiral benzaldehyde derivative; Chiral morpholine aldehyde intermediate
EINECS	Contact for details

Quality Control

Our production of 2-[(2R,6S)-2,6-Dimethyl-1,4-oxazinan-4-yl]-5-fluorobenzenecarbaldehyde adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and advanced synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to light and oxidation, prolonged exposure to air and light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.