Description

4-Ethoxy-3-(3-Methyl-Ureido)-Benzenesulfonyl Chloride is a specialized sulfonyl chloride derivative, a crucial high-purity intermediate in modern synthetic chemistry. Its primary value lies in its role as a key building block for the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on sulfonamide-based active pharmaceutical ingredients (APIs), crop protection agents, and advanced material science applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides that utilize the sulfonyl urea or sulfonamide pharmacophore.
• Chemical Research & Development: Serves as a versatile reagent for introducing the sulfonyl chloride functional group into complex molecular architectures in academic and industrial R&D settings.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized sulfonated dyes and high-performance pigments.
• Polymer Modification: Employed to functionalize polymers and resins, imparting specific chemical properties or reactivity for advanced material applications.

Basic Information

Product Name	4-Ethoxy-3-(3-Methyl-Ureido)-Benzenesulfonyl Chloride
CAS No.	678186-10-2
Molecular Formula	C10H13ClN2O4S
Molecular Weight	292.74 g/mol
Synonyms	3-(3-Methylureido)-4-ethoxybenzenesulfonyl chloride; 4-Ethoxy-3-[(methylcarbamoyl)amino]benzenesulfonyl chloride; 1-Methyl-3-(4-ethoxy-3-sulfamoylphenyl)urea sulfonyl chloride; Benzenesulfonyl chloride, 4-ethoxy-3-[(methylamino)carbonyl]amino]-; 3-(N'-Methylureido)-4-ethoxybenzenesulfonyl chloride; 4-Ethoxy-3-(N-methylureido)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-Ethoxy-3-(3-Methyl-Ureido)-Benzenesulfonyl Chloride adheres to stringent in-process and final release controls to ensure batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We operate under a cGMP-compliant quality management system suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.