Description

4-(Dimethylsulfamoyl)Benzene-1-Sulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in advanced organic synthesis. Its molecular structure, featuring both a sulfonyl chloride and a dimethylsulfamoyl group, makes it a versatile building block for constructing complex molecules with specific functional properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used to create novel sulfonylurea or sulfonamide herbicides and pesticides with tailored activity profiles.
• Functional Material Development: Serves as a monomer or cross-linking agent in the production of specialty polymers, membranes, or coatings with specific surface properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling or modifying biomolecules, such as proteins, to study biological pathways.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of advanced colorants and photographic chemicals.
• Custom Synthesis & Contract Research: A valuable reagent for research organizations and CDMOs (Contract Development and Manufacturing Organizations) developing proprietary compounds for clients.

Basic Information

Product Name	4-(Dimethylsulfamoyl)Benzene-1-Sulfonyl Chloride
CAS No.	677782-39-7
Molecular Formula	C8H10ClNO4S2
Molecular Weight	283.75 g/mol
Synonyms	4-(Dimethylsulfamoyl)benzenesulfonyl chloride; N,N-Dimethyl-4-(chlorosulfonyl)benzenesulfonamide; p-(Dimethylsulfamoyl)benzenesulfonyl chloride; 4-(N,N-Dimethylsulfamoyl)phenylsulfonyl chloride; Benzenesulfonyl chloride, 4-(dimethylsulfamoyl)-; 4-(Dimethylsulfamoyl)phenyl sulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-(Dimethylsulfamoyl)Benzene-1-Sulfonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.