Description

4-[3-(4-Fluoro-Phenyl)-Ureido]-2-Methyl-Benzene Sulfonyl Chloride is a high-purity sulfonyl chloride derivative and a critical pharmaceutical intermediate. This compound matters for its role as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in targeted therapeutic areas. It is primarily needed by research institutions and manufacturers in the global pharmaceutical and fine chemical industries for developing new drug candidates and scaling up production processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel sulfonamide-based active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the development of enzyme inhibitors for therapeutic applications.
• Chemical Biology Probes: Serves as a reactive handle for labeling and studying biological systems.
• Library Synthesis: Employed in combinatorial and medicinal chemistry for creating diverse compound libraries for screening.
• Custom Synthesis: A building block for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals.

Basic Information

Product Name	4-[3-(4-Fluoro-Phenyl)-Ureido]-2-Methyl-Benzene Sulfonyl Chloride
CAS No.	677327-10-5
Molecular Formula	C14H12ClFN2O3S
Molecular Weight	342.77 g/mol
Synonyms	4-[3-(4-Fluorophenyl)ureido]-2-methylbenzenesulfonyl chloride; 2-Methyl-4-[(4-fluorophenyl)carbamoylamino]benzenesulfonyl chloride; 4-(3-(4-Fluorophenyl)ureido)-2-methylbenzenesulfonyl chloride; 4-(N'-(4-Fluorophenyl)ureido)-2-methylbenzenesulfonyl chloride; 677327-10-5; Benzenesulfonyl chloride, 4-[[[(4-fluorophenyl)amino]carbonyl]amino]-2-methyl-
EINECS	Contact for details

Quality Control

Our 4-[3-(4-Fluoro-Phenyl)-Ureido]-2-Methyl-Benzene Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.