Description

4-[3-(4-Bromo-Phenyl)-Ureido]-2-Methyl-Benzenesulfonyl Chloride is a specialized sulfonyl chloride derivative, a crucial building block in advanced organic synthesis. Its molecular structure makes it a valuable reagent for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of biologically active molecules, including potential kinase inhibitors and receptor antagonists.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Peptide Mimetics & Conjugation: Serves as a sulfonylation agent for modifying amino acids or peptides to alter their properties or create targeted drug conjugates.
• Material Science: Building block for synthesizing specialized polymers or dyes with specific sulfonamide functionalities.
• Chemical Biology Probes: Utilized in creating activity-based probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	4-[3-(4-Bromo-Phenyl)-Ureido]-2-Methyl-Benzenesulfonyl Chloride
CAS No.	677327-02-5
Molecular Formula	C14H12BrClN2O3S
Molecular Weight	403.68 g/mol
Synonyms	4-[3-(4-Bromophenyl)ureido]-2-methylbenzenesulfonyl chloride; 2-Methyl-4-[[(4-bromophenyl)amino]carbonylamino]benzenesulfonyl chloride; 4-[(4-Bromophenyl)carbamoylamino]-2-methylbenzenesulfonyl chloride; 1-(4-Bromo-phenyl)-3-(2-methyl-4-sulfamoyl-phenyl)-urea sulfonyl chloride; CAS 677327-02-5
EINECS	Contact for details

Quality Control

Our production of 4-[3-(4-Bromo-Phenyl)-Ureido]-2-Methyl-Benzenesulfonyl Chloride adheres to stringent quality protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure consistency and reliability for your critical research and development work. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.