Description

4-(3-Methyl-Ureido)-Benzenesulfonyl Chloride is a specialized sulfonyl chloride derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its reactive sulfonyl chloride group, which enables the efficient introduction of the 4-(3-methylureido)benzenesulfonyl moiety into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used to create novel sulfonylurea or sulfonamide herbicides and pesticides by reacting with various amines.
• Chemical Biology Probe Development: Employed in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and target engagement.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses producing bespoke intermediates for client R&D programs.

Basic Information

Product Name	4-(3-Methyl-Ureido)-Benzenesulfonyl Chloride
CAS No.	677326-97-5
Molecular Formula	C8H9ClN2O3S
Molecular Weight	248.69 g/mol
Synonyms	4-(3-Methylureido)benzenesulfonyl chloride; 1-Methyl-3-(4-(chlorosulfonyl)phenyl)urea; 4-(N'-Methylureido)benzenesulfonyl chloride; N-Methyl-N'-(4-(chlorosulfonyl)phenyl)urea; 4-(3-Methylureido)phenylsulfonyl chloride; p-(3-Methylureido)benzenesulfonyl chloride; Urea, N-methyl-N'-[4-(chlorosulfonyl)phenyl]-
EINECS	Contact for details

Quality Control

Every batch of 4-(3-Methyl-Ureido)-Benzenesulfonyl Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.