Description

4-[3-(4-Carbamoyl-Phenyl)-Ureido]-Benzenesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key intermediate in the synthesis of complex organic molecules. Its value lies in its dual reactive sites, enabling its use as a versatile building block for creating sulfonamides and other functionalized aromatic compounds. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing targeted libraries and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel sulfonamide-based drug candidates, including kinase inhibitors and receptor antagonists.
• Agrochemical Research: Used in developing new herbicides and fungicides where the sulfonyl urea and sulfonamide motifs are prevalent.
• Chemical Biology & Proteomics: Serves as a reactive handle for bioconjugation and the development of activity-based probes targeting specific enzymes.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialized polymers with specific sulfonamide functionalities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	4-[3-(4-Carbamoyl-Phenyl)-Ureido]-Benzenesulfonyl Chloride
CAS No.	677326-89-5
Molecular Formula	C14H12ClN3O4S
Molecular Weight	353.78 g/mol
Synonyms	4-[[(4-Carbamoylphenyl)carbamoyl]amino]benzenesulfonyl chloride; 4-[3-(4-Carbamoylphenyl)ureido]benzenesulfonyl chloride; N-[(4-Carbamoylphenyl)carbamoyl]-4-chlorosulfonyl aniline; 4-Carbamoylphenylurea benzenesulfonyl chloride derivative; (4-{[(4-Carbamoylphenyl)carbamoyl]amino}phenyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-[3-(4-Carbamoyl-Phenyl)-Ureido]-Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.