Description

4-[3-(4-Nitrophenyl)Ureido]Benzenesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a sulfonyl chloride group and a nitrophenyl urea moiety, makes it a versatile building block for constructing complex molecules with specific functionalities. This compound is primarily sought by research and development laboratories and fine chemical manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting enzyme inhibition where the sulfonamide pharmacophore is essential.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its reactive sites for structural diversification.
• Dye and Pigment Chemistry: Serves as a key intermediate for creating azo dyes and other complex colorants, where the nitrophenyl group can be further modified.
• Polymer Modification: Employed to introduce sulfonamide or urea functional groups into polymer backbones, altering material properties like solubility, thermal stability, or biological activity.
• Bioconjugation and Probe Development: Utilized in biochemical research for labeling proteins or other biomolecules due to the reactivity of the sulfonyl chloride group with amines.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating libraries of novel chemical entities.

Basic Information

Item	Detail
Product Name	4-[3-(4-Nitrophenyl)Ureido]Benzenesulfonyl Chloride
CAS No.	677326-85-1
Molecular Formula	C13H10ClN3O5S
Molecular Weight	355.75 g/mol
Synonyms	4-[(4-Nitrophenyl)carbamoylamino]benzenesulfonyl chloride; N-(4-Nitrophenyl)-N'-(4-chlorosulfonylphenyl)urea; 1-(4-Nitrophenyl)-3-(4-chlorosulfonylphenyl)urea; 4-Nitrophenylurea-4'-benzenesulfonyl chloride; p-Nitrophenylureidobenzenesulfonyl chloride; (4-Nitrophenylcarbamoylamino)phenylsulfonyl chloride; 4-[(4-Nitroanilino)carbonylamino]benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4-[3-(4-Nitrophenyl)Ureido]Benzenesulfonyl Chloride is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting purity standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.