Description

2'-Fluorobiphenyl-3-Carbaldehyde is a high-purity fluorinated biphenyl derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique reactivity of the aldehyde group and the electronic influence of the fluorine substituent, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its biphenyl core for biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and transition metal complexes.
• Organic Electronic Materials: A starting material for synthesizing fluorinated organic semiconductors and charge-transport materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new fluorination reactions and cross-coupling methodologies.
• Liquid Crystal & OLED Precursor: Used in the synthesis of fluorinated cores for advanced display and lighting materials.

Basic Information

Product Name	2'-Fluorobiphenyl-3-Carbaldehyde
CAS No.	676348-33-7
Molecular Formula	C₁₃H₉FO
Molecular Weight	200.21 g/mol
Synonyms	3-Formyl-2'-fluorobiphenyl; 2'-Fluoro[1,1'-biphenyl]-3-carboxaldehyde; 2'-Fluoro-3-biphenylcarboxaldehyde; [1,1'-Biphenyl]-3-carboxaldehyde, 2'-fluoro-; 2-Fluorobiphenyl-3-carbaldehyde; Biphenyl-3-carbaldehyde, 2'-fluoro-; 2'-F-Biphenyl-3-CHO
EINECS	Contact for details

Quality Control

Our 2'-Fluorobiphenyl-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and potential for oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.