Description

3'-Fluorobiphenyl-2-Carbaldehyde is a high-purity fluorinated aromatic aldehyde building block, essential for advanced organic synthesis. Its unique structure, featuring both a biphenyl core and a formyl group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and receptor antagonist research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances bioavailability and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and advanced polymers due to its conjugated biphenyl system.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for studying biological systems.
• Cross-Coupling Reactions: The aldehyde group is a versatile handle for further functionalization via reactions like Suzuki-Miyaura or reductive amination.

Basic Information

Product Name	3'-Fluorobiphenyl-2-Carbaldehyde
CAS No.	676348-32-6
Molecular Formula	C₁₃H₉FO
Molecular Weight	200.21 g/mol
Synonyms	2-Formyl-3'-fluorobiphenyl; [1,1'-Biphenyl]-2-carboxaldehyde, 3'-fluoro-; 3'-Fluoro[1,1'-biphenyl]-2-carbaldehyde; 3'-Fluoro-2-biphenylcarboxaldehyde; 2-(3-Fluorophenyl)benzaldehyde; 3-Fluorobiphenyl-2-carboxaldehyde; 3'-F-Biphenyl-2-Carboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3'-Fluorobiphenyl-2-Carbaldehyde is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and scale-up. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed HPLC/GC purity, NMR, and mass spec data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.