Description

4'-Trifluoromethoxy-Biphenyl-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its biphenyl core and functional aldehyde group. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry where its trifluoromethoxy moiety is prized for enhancing metabolic stability and lipophilicity. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethoxy group can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs), due to its conjugated biphenyl system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical synthesis projects.

Basic Information

Product Name	4'-Trifluoromethoxy-Biphenyl-3-Carbaldehyde
CAS No.	675596-34-6
Molecular Formula	C14H9F3O2
Molecular Weight	266.22 g/mol
Synonyms	3-Formyl-4'-(trifluoromethoxy)biphenyl; [1,1'-Biphenyl]-3-carboxaldehyde, 4'-(trifluoromethoxy)-; 4'-(Trifluoromethoxy)[1,1'-biphenyl]-3-carbaldehyde; Biphenyl-3-carbaldehyde, 4'-trifluoromethoxy-; 4'-Trifluoromethoxy-3-biphenylcarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4'-Trifluoromethoxy-Biphenyl-3-Carbaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its properties, this material should be stored under an inert atmosphere to prevent oxidation and kept away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.