Description

5-Bromo-3-Fluoropyridine-2-Carbaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated and aldehyde-substituted structure makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by material scientists exploring new functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological mechanisms.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Bromo-3-Fluoropyridine-2-Carbaldehyde
CAS No.	669066-93-7
Molecular Formula	C6H3BrFNO
Molecular Weight	204.00 g/mol
Synonyms	2-Bromo-5-fluoropyridine-3-carboxaldehyde; 3-Fluoro-5-bromopyridine-2-carbaldehyde; 5-Bromo-3-fluoropicolinaldehyde; 2-Formyl-5-bromo-3-fluoropyridine; 5-Bromo-3-fluoro-2-pyridinecarboxaldehyde; 669066-93-7; 3-Fluoro-5-bromo-2-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Fluoropyridine-2-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.