Description

(2-Fluoropyridin-4-Yl)Methanamine Dihydrochloride is a high-purity fluorinated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile amine synthon, enabling the introduction of a functionalized heterocyclic scaffold into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluoropyridine moiety.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science: A building block for advanced polymers and functional materials requiring specific electronic or binding properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and scale-up activities.

Basic Information

Product Name	(2-Fluoropyridin-4-Yl)Methanamine Dihydrochloride
CAS No.	667906-60-7
Molecular Formula	C6H8Cl2FN2
Molecular Weight	207.05 g/mol
Synonyms	4-(Aminomethyl)-2-fluoropyridine dihydrochloride; 2-Fluoro-4-(aminomethyl)pyridine dihydrochloride; (2-Fluoro-4-pyridinyl)methanamine dihydrochloride; 4-(Aminomethyl)-2-fluoropyridine hydrochloride (1:2); 2-Fluoropyridin-4-ylmethanamine dihydrochloride; 2-Fluoro-4-pyridinemethanamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (2-Fluoropyridin-4-Yl)Methanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.