Description

Indirubin-3-Monoxime is a potent and selective small molecule inhibitor with significant biological activity. This compound is a derivative of indirubin, a natural product found in traditional Chinese medicine, and is valued for its targeted mechanism of action in research and development. It is primarily utilized by researchers in the pharmaceutical and biotechnology sectors for investigating cellular pathways and developing novel therapeutic agents. Its high purity and consistent quality are critical for ensuring reliable and reproducible experimental results.

Application

• Pharmaceutical Research & Development: As a key intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutics targeting specific kinases.
• Biochemical Research: Used as a selective inhibitor in cell biology and signal transduction studies to elucidate disease mechanisms.
• Academic Research: A vital tool compound in university and institutional labs for studying cell cycle regulation and apoptosis.
• Preclinical Studies: Employed in in vitro and in vivo models to assess efficacy and pharmacokinetic properties of drug candidates.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Indirubin-3-Monoxime
CAS No.	667463-82-3
Molecular Formula	C16H10N2O2
Molecular Weight	262.27 g/mol
Synonyms	Indirubin 3-monoxime; 2,3-Bis(indol-3-yl)maleimide N-oxide; 3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one oxime; Indirubin-3-oxime; GSK-3β Inhibitor IX; 6BIO; (E)-6-Bromoindirubin-3'-oxime (Note: 6BIO is a brominated derivative, often associated); Indirubin derivative
EINECS	Contact for details

Quality Control

Our Indirubin-3-Monoxime is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Red to reddish-brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.