Description

Tenovin-2 is a potent and selective small molecule inhibitor of SIRT1 and SIRT2, key enzymes in the sirtuin family involved in cellular regulation. This compound matters for researchers and developers as it serves as a critical chemical tool for probing the role of sirtuin deacetylases in pathways related to aging, metabolism, and oncology. It is primarily needed by professionals in pharmaceutical R&D, academic biochemistry laboratories, and biotechnology companies focused on epigenetic research and drug discovery.

Application

• Biochemical Research: Used as a reference standard and probe compound in studies of sirtuin biology and epigenetic regulation.
• Drug Discovery: Serves as a lead compound or pharmacophore model for developing novel therapeutics targeting sirtuin-related diseases.
• Oncology Research: Employed in in vitro and cellular assays to investigate the role of SIRT1/2 in cancer cell survival, proliferation, and tumorigenesis.
• Metabolic Disease Studies: Applied in research models to understand sirtuin functions in metabolic pathways, including glucose and lipid homeostasis.
• Neurodegenerative Disease Research: Utilized to explore the potential neuroprotective or pathogenic roles of sirtuins in conditions like Alzheimer's and Parkinson's disease.
• Anti-aging Research: A key tool in studying cellular senescence, stress resistance, and lifespan extension mechanisms mediated by sirtuin activity.

Basic Information

Product Name	Tenovin-2
CAS No.	666211-30-9
Molecular Formula	C₁₉H₂₀N₂OS
Molecular Weight	324.44 g/mol
Synonyms	N-(2-Mercaptophenyl)-2-(phenylamino)benzamide; 2-[(2-Mercaptophenyl)carbamoyl]-N-phenylaniline; Tenovin 2; Tenovin2; SIRT1/2 Inhibitor III; Sirtuin Inhibitor, Tenovin-2
EINECS	Contact for details

Quality Control

Our Tenovin-2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity confirmation and identity verification by spectroscopic methods (NMR, MS). Certificates of Analysis (COA) detailing batch-specific results are available upon request to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.