Description

2-Fluoro-4,5-Dimethoxybenzene-1-Sulfonyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its value lies in its dual functionality as both a sulfonylating agent and a fluorinated aromatic scaffold, enabling the precise construction of complex molecules. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used to build fluorinated sulfonyl-containing molecules for next-generation herbicides, fungicides, and pesticides.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) and molecular tags for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the introduction of a fluorinated sulfonyl chloride moiety.
• Dye & Pigment Intermediate: Facilitates the production of specialized fluorinated dyes and colorants with enhanced properties.

Basic Information

Item	Detail
Product Name	2-Fluoro-4,5-Dimethoxybenzene-1-Sulfonyl Chloride
CAS No.	656806-43-8
Molecular Formula	C8H8ClFO4S
Molecular Weight	254.66 g/mol
Synonyms	4,5-Dimethoxy-2-fluorobenzenesulfonyl chloride; 2-Fluoro-4,5-dimethoxybenzenesulfonyl chloride; 1-(Chlorosulfonyl)-2-fluoro-4,5-dimethoxybenzene; 656806-43-8; 2-Fluoro-4,5-dimethoxy-1-sulfonyl chloride benzene; 4,5-Dimethoxy-2-fluorophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4,5-Dimethoxybenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.