Description

3',5'-Difluorobiphenyl-3-Carbaldehyde is a high-purity fluorinated biphenyl derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the precise molecular architecture that enables the construction of complex, functionalized molecules for demanding applications. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce specific fluorinated aromatic motifs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics where the difluorobiphenyl scaffold is pharmacologically relevant.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, leveraging the stability and bioactivity imparted by the fluorinated aromatic system.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), contributing to improved electronic and optical properties.
• Organic Synthesis & Catalysis: Employed as a versatile aldehyde component in cross-coupling reactions (e.g., Suzuki, Heck) and as a substrate for the development of novel chiral ligands and catalysts.
• Polymer & Material Science: Acts as a monomer or functionalization agent for creating high-performance polymers with enhanced thermal stability, chemical resistance, and specific surface properties.

Basic Information

Product Name	3',5'-Difluorobiphenyl-3-Carbaldehyde
CAS No.	656306-74-0
Molecular Formula	C13H8F2O
Molecular Weight	218.20 g/mol
Synonyms	3-(3,5-Difluorophenyl)benzaldehyde; [1,1'-Biphenyl]-3-carboxaldehyde, 3',5'-difluoro-; 3',5'-Difluoro[1,1'-biphenyl]-3-carbaldehyde; 3-Formyl-3',5'-difluorobiphenyl; (3',5'-Difluorobiphenyl-3-yl)methanal
EINECS	Contact for details

Quality Control

Our 3',5'-Difluorobiphenyl-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere to prevent oxidation and handled under controlled conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.