Description

(3Ar,4R,5R,6As)-4-[(1E)-4-(3-Chlorophenoxy)-3-Hydroxy-1-Buten-1-Yl]Hexahydro-5-Hydroxy-2H-Cyclopenta[B]Furan-2-One is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its complex molecular architecture, which serves as a critical building block for the synthesis of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or crop protection products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex target molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to explore new chemical entities for various disease targets.
• Process Chemistry Development: Serves as a starting material or advanced intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Agrochemical Synthesis: Potential building block for the development of new herbicides, fungicides, or insecticides with specific modes of action.
• Academic & Institutional Research: Employed in university and government laboratories for methodological studies in asymmetric synthesis and natural product analog development.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services for client projects.

Basic Information

Product Name	(3Ar,4R,5R,6As)-4-[(1E)-4-(3-Chlorophenoxy)-3-Hydroxy-1-Buten-1-Yl]Hexahydro-5-Hydroxy-2H-Cyclopenta[B]Furan-2-One
CAS No.	652152-39-1
Molecular Formula	C17H19ClO5
Molecular Weight	338.78 g/mol
Synonyms	4-[(1E)-4-(3-Chlorophenoxy)-3-hydroxybut-1-en-1-yl]hexahydro-5-hydroxy-2H-cyclopenta[b]furan-2-one; (3aR,4R,5R,6aS)-4-[(1E)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]hexahydro-5-hydroxy-2H-cyclopenta[b]furan-2-one; Cyclopenta[b]furan-2-one derivative; Prostaglandin intermediate analog; Chiral chlorophenoxy butenyl lactone
EINECS	Contact for details

Quality Control

Every batch of (3Ar,4R,5R,6As)-4-[(1E)-4-(3-Chlorophenoxy)-3-Hydroxy-1-Buten-1-Yl]Hexahydro-5-Hydroxy-2H-Cyclopenta[B]Furan-2-One is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including chiral purity verification, to ensure compliance with research and development standards. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.