Description

Glycogen Phosphorylase Inhibitor CAS NO 648926-15-2 is a potent and selective small molecule inhibitor of the glycogen phosphorylase enzyme, a key regulator of glycogen metabolism. This compound is of significant value for biochemical research and drug discovery targeting metabolic disorders such as type 2 diabetes. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on metabolic pathway analysis and therapeutic development.

Application

• Biochemical Research: Used as a critical tool compound to study glycogenolysis, glucose homeostasis, and hepatic glucose output in cellular and enzymatic assays.
• Drug Discovery Programs: Serves as a lead compound or reference standard in the development of novel anti-diabetic agents targeting glycogen phosphorylase.
• Metabolic Disorder Studies: Applied in preclinical research to investigate the pathophysiology and potential treatment of type 2 diabetes and related metabolic syndromes.
• Enzyme Kinetics & Mechanism: Utilized to elucidate the inhibition kinetics and binding mode of molecules to the glycogen phosphorylase enzyme.
• Cell-Based Screening Assays: Employed as a positive control in high-throughput screening (HTS) campaigns to identify new modulator scaffolds.
• Academic & Institutional Research: Supports fundamental research in biochemistry, molecular biology, and physiology departments.

Basic Information

Product Name	Glycogen Phosphorylase Inhibitor
CAS No.	648926-15-2
Molecular Formula	C₁₉H₂₀N₄O₃
Molecular Weight	352.39 g/mol
Synonyms	CP-91149; 1,4-Dideoxy-1,4-imino-D-arabinitol Derivative; Glycogen Phosphorylase Inhibitor CP-91149; 5-Chloro-1H-indole-2-carboxylic Acid [1-(4-Fluorobenzyl)-2-(4-Hydroxypiperidin-1-yl)-2-Oxoethyl]amide; (R)-5-Chloro-1H-indole-2-carboxylic Acid [1-(4-Fluorobenzyl)-2-(4-Hydroxypiperidin-1-yl)-2-Oxoethyl]amide; GP Inhibitor 648926-15-2; Hepatic Glycogen Phosphorylase Inhibitor
EINECS	Contact for details

Quality Control

Our Glycogen Phosphorylase Inhibitor is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.