Description

2,3-Difluoro-4-Bromobenzaldehyde is a high-purity fluorinated and halogenated aromatic aldehyde building block. This compound is valued for its unique reactivity profile, where the aldehyde group and strategically placed fluorine and bromine atoms enable precise synthetic modifications. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging the bioactivity imparted by the fluorine and bromine substituents.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals and organic semiconductors, where fluorination tunes electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated benzaldehyde derivatives.

Basic Information

Product Name	2,3-Difluoro-4-Bromobenzaldehyde
CAS No.	644985-24-0
Molecular Formula	C7H3BrF2O
Molecular Weight	220.99 g/mol
Synonyms	4-Bromo-2,3-difluorobenzaldehyde; 2,3-Difluoro-4-bromobenzenecarboxaldehyde; 4-Bromo-2,3-difluorobenzenecarbaldehyde; Benzaldehyde, 4-bromo-2,3-difluoro-; 644985-24-0; 2,3-Difluoro-4-bromo-benzaldehyde; 4-Bromo-2,3-difluoro benzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2,3-Difluoro-4-Bromobenzaldehyde is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency. Our standard quality commitment includes rigorous testing for identity, purity, and impurity profiles using advanced techniques like HPLC, GC, and NMR. Certificates of Analysis (COA) are available for all shipments, detailing batch-specific results against agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.