Description

3-Methylisoquinoline-5-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a crucial building block in advanced organic synthesis. Its primary value lies in its reactivity as a sulfonylation reagent, enabling the introduction of the 3-methylisoquinoline-5-sulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs), intermediates, and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides.
• Dye and Pigment Manufacturing: Serves as a precursor for specialized dyes and functional pigments.
• Material Science Research: Employed in the creation of advanced polymers and functional materials.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in proteomics and biochemical research.
• Custom Synthesis: A versatile reagent for contract research organizations (CROs) and fine chemical suppliers.

Basic Information

Product Name	3-Methylisoquinoline-5-Sulfonyl Chloride
CAS No.	640290-02-4
Molecular Formula	C₁₀H₈ClNO₂S
Molecular Weight	237.69 g/mol
Synonyms	5-(Chlorosulfonyl)-3-methylisoquinoline; 3-Methyl-5-isoquinolinesulfonyl chloride; 3-Methylisoquinoline-5-sulphonyl chloride; Isoquinoline-5-sulfonyl chloride, 3-methyl-; 640290-02-4; 3-MIQ-5-SO₂Cl
EINECS	Contact for details

Quality Control

Our 3-Methylisoquinoline-5-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.