Description

4-Bromo-3-Iodobenzotrifluoride is a high-value halogenated aromatic building block characterized by its trifluoromethyl and two distinct halogen substituents. This compound is essential for facilitating advanced cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki, Stille, and Negishi cross-coupling reactions for creating biaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides requiring specific halogenated aromatic cores.
• Material Science: Serves as a monomer or functionalization agent for creating specialty polymers and liquid crystals with unique electronic properties.
• Organic Electronics: Employed in the synthesis of charge-transport materials and emitters for OLED (Organic Light-Emitting Diode) applications.
• Chemical Research: A versatile reagent for method development in catalysis and exploring new synthetic pathways in academic and industrial labs.
• Fluorinated Compound Libraries: Integral for building diverse screening libraries in medicinal chemistry due to the desirable properties imparted by the trifluoromethyl group.

Basic Information

Product Name	4-Bromo-3-Iodobenzotrifluoride
CAS No.	640280-28-0
Molecular Formula	C7H3BrF3I
Molecular Weight	350.90 g/mol
Synonyms	1-Bromo-2-iodo-4-(trifluoromethyl)benzene; 4-Bromo-3-iodo-α,α,α-trifluorotoluene; 2-Iodo-4-bromobenzotrifluoride; Benzene, 1-bromo-2-iodo-4-(trifluoromethyl)-; 4-Bromo-3-iodobenzotrifluoride; 3-Iodo-4-bromobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Iodobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged manipulations.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.