Description

4-Fluoro-3-Methylbenzenesulfonyl Chloride is a versatile and high-purity sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its reactivity as a sulfonylation agent, enabling the introduction of the sulfonyl functional group to create novel compounds with specific properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and pesticides that require the sulfonyl moiety for bioactivity.
• Material Science Research: Employed in the development of specialty polymers, dyes, and liquid crystals where sulfonyl groups modify material properties.
• Chemical Biology Probes: Acts as a reagent for labeling and modifying biomolecules in proteomics and biochemical research.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom chemical synthesis services and scale-up production for various industrial applications.

Basic Information

Product Name	4-Fluoro-3-Methylbenzenesulfonyl Chloride
CAS No.	629672-19-1
Molecular Formula	C7H6ClFO2S
Molecular Weight	208.64 g/mol
Synonyms	3-Methyl-4-fluorobenzenesulfonyl chloride; 4-Fluoro-3-methylbenzene-1-sulfonyl chloride; 1-(Chlorosulfonyl)-4-fluoro-3-methylbenzene; 4-Fluoro-m-toluenesulfonyl chloride; 3-Methyl-4-fluorophenylsulfonyl chloride; 4-Fluoro-3-methylphenyl sulfonyl chloride; p-Fluoro-m-toluenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.