Description

Ethanone, 2-Chloro-1-(3-Fluoro-4-Methylphenyl)- (9Ci) is a specialized aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated and substituted phenyl structure, which makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a critical building block for developing new-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its rigid molecular framework.
• Chemical Research & Development: Employed in methodological studies for cross-coupling reactions, halogen-metal exchanges, and other advanced synthetic transformations.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific, high-purity halogenated intermediates.

Basic Information

Product Name	Ethanone, 2-Chloro-1-(3-Fluoro-4-Methylphenyl)- (9Ci)
CAS No.	627463-24-5
Molecular Formula	C9H8ClFO
Molecular Weight	186.61 g/mol
Synonyms	2-Chloro-1-(3-fluoro-4-methylphenyl)ethanone; 2-Chloro-3'-fluoro-4'-methylacetophenone; 1-(3-Fluoro-4-methylphenyl)-2-chloroethanone; 2-Chloro-1-(3-fluoro-4-methylphenyl)ethan-1-one; α-Chloro-3-fluoro-4-methylacetophenone; 3-Fluoro-4-methylphenacyl chloride
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Production of Ethanone, 2-Chloro-1-(3-Fluoro-4-Methylphenyl)- (9Ci) adheres to current Good Manufacturing Practices (cGMP) where applicable, ensuring batch-to-batch consistency and reliability. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.