Description

3-Iodo-4-(Trifluoromethyl)-Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining an iodine substituent with a trifluoromethyl group on the pyridine ring, makes it indispensable for introducing specific functionalities into target molecules. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, herbicides, and fungicides, leveraging the biological activity imparted by the halogen and fluorine groups.
• Material Science: Serves as a precursor for synthesizing functionalized ligands, organic electronic materials, and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Negishi) due to the reactive iodine atom, enabling efficient carbon-carbon bond formation.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3-Iodo-4-(Trifluoromethyl)-Pyridine
CAS No.	625115-02-8
Molecular Formula	C6H3F3IN
Molecular Weight	272.99 g/mol
Synonyms	4-(Trifluoromethyl)-3-iodopyridine; 3-Iodo-4-trifluoromethylpyridine; Pyridine, 3-iodo-4-(trifluoromethyl)-; 3-Iodo-α,α,α-trifluoro-4-picoline
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-4-(Trifluoromethyl)-Pyridine is manufactured and tested under strict quality management protocols to ensure consistency and purity for demanding synthetic applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.