Description

Staurosporine is a potent, cell-permeable alkaloid and a broad-spectrum protein kinase inhibitor. This high-purity compound is essential for biochemical research, particularly in the study of cellular signaling pathways, apoptosis, and cell cycle regulation. It is a critical tool for researchers and developers in the pharmaceutical, biotechnology, and life sciences industries.

Application

• Biochemical Research: A primary tool for studying protein kinase C (PKC) and other serine/threonine kinases in signal transduction pathways.
• Apoptosis Induction: Used to induce programmed cell death in various cell lines for cancer research and therapeutic mechanism studies.
• Cell Cycle Analysis: Employed to arrest cells at specific phases (e.g., G1 phase) to investigate cell cycle control and checkpoint mechanisms.
• Pharmaceutical Screening: Serves as a reference standard and positive control in high-throughput screening for novel kinase inhibitor drugs.
• Neuroscience Research: Applied in studies of neuronal differentiation, survival, and neurodegenerative disease models.
• Academic & Industrial R&D: Fundamental reagent for basic research in molecular biology, cell biology, and drug discovery pipelines.

Basic Information

Product Name	Staurosporine
CAS No.	622996-74-1
Molecular Formula	C28H26N4O3
Molecular Weight	466.54 g/mol
Synonyms	Antibiotic AM-2282; STS; Staurosporin; AM-2282; (-)-Staurosporine; Staurosporine, microbial; NSC 623397; 8,13-Epoxy-1H,6H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, (1S,13S,15R)-
EINECS	Contact for details

Quality Control

Our Staurosporine is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.