Description

7-Epi Clindamycin 2-Phosphate is a chemically modified derivative of the antibiotic clindamycin, specifically the 7-epimer of its 2-phosphate ester. This compound is of significant interest in pharmaceutical research and development as a key intermediate or reference standard for the synthesis and quality control of advanced antibiotic formulations. It is primarily utilized by research institutions, pharmaceutical manufacturers, and analytical laboratories engaged in the development of novel antibacterial agents, metabolic studies, and impurity profiling. The precise chemical structure of this epimer makes it a critical tool for ensuring the purity and efficacy of related clindamycin-based pharmaceutical products.

Application

• Pharmaceutical research as a reference standard for analytical method development and validation.
• Key chemical intermediate in the synthesis of novel clindamycin analogs and prodrugs.
• Impurity profiling and identification in the quality control of clindamycin phosphate active pharmaceutical ingredients (APIs).
• Metabolic and pharmacokinetic studies to understand the behavior of clindamycin derivatives.
• Use in academic and industrial laboratories for structure-activity relationship (SAR) research.
• Preparation of in-house calibration standards for high-performance liquid chromatography (HPLC) and mass spectrometry (MS) analysis.

Basic Information

Product Name	7-Epi Clindamycin 2-Phosphate
CAS No.	620181-05-7
Molecular Formula	C18H34ClN2O8PS
Molecular Weight	504.94 g/mol
Synonyms	7-Epimer of Clindamycin 2-Phosphate; (2S,4R)-N-[(1S,2S)-2-Chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropyl]-1-methyl-4-propylpyrrolidine-2-carboxamide 2-(Dihydrogen phosphate); Clindamycin 7-Epimer 2-Phosphate; 7-Epi Clindamycin Phosphate; 7-Epimeric Clindamycin 2-Phosphate
EINECS	Contact for details

Quality Control

Our 7-Epi Clindamycin 2-Phosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity research-grade standards. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the specific results for all tested parameters to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.