Description

Sb-743291 is a high-purity, small molecule chemical compound with significant utility in advanced research and development. This compound is valued for its role as a potent and selective inhibitor, making it a critical tool for investigating specific biological pathways and target validation. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on drug discovery and biochemical mechanism studies. The compound is supplied under stringent quality controls to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: Used as a selective inhibitor in enzymatic and cellular assays to study specific kinase activity and signal transduction pathways.
• Drug Discovery & Development: Serves as a key pharmacological tool for target validation, hit-to-lead optimization, and preclinical studies in oncology and other therapeutic areas.
• Academic Research: Employed in university and institutional labs for fundamental research into cell biology, apoptosis, and protein function.
• High-Throughput Screening (HTS): Acts as a reference standard or positive control in automated screening platforms to identify novel therapeutic compounds.
• Proteomics & Molecular Biology: Utilized to modulate specific protein functions to understand protein-protein interactions and downstream effects.

Basic Information

Product Name	Sb-743291
CAS No.	618430-39-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	SB-743921; SB 743921; SB743921; 4-[[(7S)-6,7,8,9-Tetrahydro-7-(1-oxopropyl)-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl]amino]-2-fluoro-5-methylphenol; KSP Inhibitor SB-743921; Eg5 Kinesin Inhibitor SB-743921
EINECS	Contact for details

Quality Control

Our Sb-743291 is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (NMR, IR, MS) and purity determination by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.