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1-(2-Fluorophenyl)-3-(Pyridin-3-Yl)-1H-Pyrazole-4-Carbaldehyde CAS NO 618101-79-4


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CAS No.:618101-79-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(2-Fluorophenyl)-3-(Pyridin-3-Yl)-1H-Pyrazole-4-Carbaldehyde is a high-purity fluorinated pyrazole derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular architecture, which combines a fluorinated phenyl ring with a pyridine-pyrazole core, enabling the construction of complex molecules with targeted biological and material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing new active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic research.
  • Agrochemical Development: Used in creating new-generation pesticides and herbicides, where the fluorine atom and heterocyclic structure enhance bioactivity and environmental stability.
  • Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or molecular sensors, due to its conjugated system.
  • Chemical Biology Probes: Employed in the design of fluorescent tags or activity-based probes for studying enzymatic processes and cellular pathways.
  • Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name 1-(2-Fluorophenyl)-3-(Pyridin-3-Yl)-1H-Pyrazole-4-Carbaldehyde
CAS No. 618101-79-4
Molecular Formula C15H10FN3O
Molecular Weight 267.26 g/mol
Synonyms 3-Pyridinyl-1-(2-fluorophenyl)-1H-pyrazole-4-carboxaldehyde; 1-(2-Fluorophenyl)-3-(3-pyridinyl)-1H-pyrazole-4-carbaldehyde; 1H-Pyrazole-4-carboxaldehyde, 1-(2-fluorophenyl)-3-(3-pyridinyl)-; 618101-79-4; 1-(2-Fluorophenyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde; 3-(1-(2-Fluorophenyl)-1H-pyrazol-3-yl)pyridine-4-carbaldehyde
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Quality Control

Our production of 1-(2-Fluorophenyl)-3-(Pyridin-3-Yl)-1H-Pyrazole-4-Carbaldehyde adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For projects requiring specific regulatory support, we can discuss compliance with cGMP, ICH guidelines, and other relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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