Description

Lorcaserin 5-Methyl Isomer Hcl is a specific stereoisomer of the pharmaceutical compound Lorcaserin hydrochloride. This high-purity chemical intermediate is critical for research and development in medicinal chemistry, particularly for studying structure-activity relationships and metabolic pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on developing and analyzing novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Serves as a critical analytical standard for method development and validation in HPLC, LC-MS, and other chromatographic techniques.
• Metabolite Research: Used in studies to identify, synthesize, and characterize potential metabolites of Lorcaserin for toxicology and pharmacokinetic profiling.
• Medicinal Chemistry R&D: A key building block for synthesizing novel chemical entities and analogs to explore new therapeutic applications and patent landscapes.
• Impurity Profiling: Essential for identifying and quantifying isomeric impurities in active pharmaceutical ingredient (API) batches to ensure compliance with ICH guidelines.
• Bioanalytical Studies: Employed in the development of sensitive assays for the detection and quantification of Lorcaserin and its isomers in biological matrices.
• Process Chemistry: Used in the optimization of synthetic routes for Lorcaserin API, helping to understand and control isomer formation during manufacturing.

Basic Information

Product Name	Lorcaserin 5-Methyl Isomer Hcl
CAS No.	616201-89-9
Molecular Formula	C11H15ClN2O
Molecular Weight	226.70 g/mol
Synonyms	(1R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride; (R)-Lorcaserin hydrochloride; (R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine HCl; Belviq Isomer; APD356 Isomer; BVT-933 Isomer; 5-Methyl Lorcaserin HCl; R-Lorcaserin HCl
EINECS	Contact for details

Quality Control

Our Lorcaserin 5-Methyl Isomer Hcl is manufactured under strict quality control protocols to ensure high chemical purity and batch-to-batch consistency suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards for research chemicals, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.