Description

Lorcaserina CAS NO 616201-80-0 is a selective serotonin 2C (5-HT2C) receptor agonist, a pharmaceutical compound of significant interest in therapeutic development. Its primary value lies in its targeted mechanism of action, which offers a high degree of specificity for modulating appetite and metabolic pathways. This makes it a critical intermediate and active pharmaceutical ingredient (API) for research and manufacturing entities focused on metabolic disorders. Key stakeholders include pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and companies developing novel treatments for obesity and related conditions.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of anti-obesity medications.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.
• Biochemical Research for studying serotonin receptor pharmacology and signaling pathways.
• Preclinical and Clinical Development of new therapeutic agents targeting the 5-HT2C receptor.
• Process Chemistry and scale-up synthesis for commercial API production.
• Formulation Development for creating various dosage forms such as tablets or capsules.

Basic Information

Product Name	Lorcaserina
CAS No.	616201-80-0
Molecular Formula	C11H14ClN
Molecular Weight	195.69 g/mol
Synonyms	Lorcaserin; Belviq; APD-356; (1R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine; (R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine; 3-Benzazepine, 8-chloro-1-methyl-2,3,4,5-tetrahydro-, (1R)-; BVT-933; 5-HT2C receptor agonist
EINECS	Contact for details

Quality Control

Our Lorcaserina is manufactured under strict quality management systems to meet the exacting standards of the pharmaceutical industry. Every batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and chiral analysis to ensure enantiomeric purity. A Certificate of Analysis (COA) is provided with each shipment, detailing compliance with agreed specifications. We support development from research to commercial scale with consistent quality and full regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% (R-enantiomer)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.