Description

Glycerol Phenylbutyrate is a synthetic chemical compound primarily used as a prodrug in advanced pharmaceutical applications. This compound is critical for its role in the management of specific metabolic disorders, offering a targeted therapeutic approach. It is essential for manufacturers in the pharmaceutical and fine chemical sectors requiring high-purity intermediates for active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: Key starting material or prodrug in the synthesis of treatments for urea cycle disorders.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the manufacture of prescription medications for hyperammonemia.
• Metabolic Disorder Research: Serves as a critical compound in biochemical and pharmacological R&D for studying nitrogen metabolism pathways.
• Fine Chemical Production: Employed in the synthesis of complex organic molecules requiring a glycerol phenylbutyrate moiety.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for drug testing and validation.

Basic Information

Product Name	Glycerol Phenylbutyrate
CAS No.	611168-24-2
Molecular Formula	C19H20O5
Molecular Weight	328.36 g/mol
Synonyms	GPB; Glycerol Phenylbutanoate; 1,2,3-Propanetriol, 1-phenylbutanoate; Phenylbutyryl Glycerol; RAVICTI (Trade Name); Glycerol Tri(phenylbutyrate); Benzenepropanoic acid, 4-phenyl-, 2,3-dihydroxypropyl ester; (R)-Glycerol 1-(4-phenylbutyrate)
EINECS	Contact for details

Quality Control

Our Glycerol Phenylbutyrate is manufactured under strict quality systems to meet the rigorous standards required for pharmaceutical intermediates. We provide comprehensive quality assurance, with testing protocols aligned with ICH guidelines. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.