Description

8-Fluoro-5-Nitroisoquinoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique molecular architecture, featuring both a fluorine substituent and a nitro group on the isoquinoline scaffold, makes it a critical intermediate for the development of novel pharmacologically active compounds. This compound is primarily sought after by research scientists and process chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting kinases and other enzymes.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated nitro-isoquinoline core.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology: Employed as a molecular probe or a tagged scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Academic & Contract Research: Essential for fundamental research in heterocyclic chemistry and the development of novel synthetic methodologies.

Basic Information

Product Name	8-Fluoro-5-Nitroisoquinoline
CAS No.	608515-46-4
Molecular Formula	C9H5FN2O2
Molecular Weight	192.15 g/mol
Synonyms	5-Nitro-8-fluoroisoquinoline; 8-Fluoro-5-nitro-isoquinoline; Isoquinoline, 8-fluoro-5-nitro-; 608515-46-4; 8-Fluoro-5-nitro-1-azanaphthalene
EINECS	Contact for details

Quality Control

Our 8-Fluoro-5-Nitroisoquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, prolonged exposure to light, air, or moisture should be avoided. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.