Description

2-Propanone,1-(5-Fluoro-3-Pyridinyl)-(9Ci) is a specialized fluorinated pyridinyl ketone derivative, serving as a crucial advanced intermediate in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecular architectures, particularly for active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity building block is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates to drive innovation.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluoropyridine moiety enhances biological activity and stability.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Ligand and Catalyst Preparation: Utilized in the development of specialized ligands and organocatalysts for asymmetric synthesis and other catalytic processes.
• Material Science Precursor: Potential intermediate in the synthesis of functionalized polymers or organic electronic materials.

Basic Information

Product Name	2-Propanone,1-(5-Fluoro-3-Pyridinyl)-(9Ci)
CAS No.	605681-20-7
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	1-(5-Fluoropyridin-3-yl)propan-1-one; 3-Acetyl-5-fluoropyridine; 5-Fluoro-3-acetylpyridine; 1-(5-Fluoro-3-pyridinyl)ethanone; 5-Fluoronicotinoyl methyl ketone; 605681-20-7; Ethanone, 1-(5-fluoro-3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 2-Propanone,1-(5-Fluoro-3-Pyridinyl)-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.