Description

4-Carboxy-3-Fluorobenzaldehyde is a versatile fluorinated aromatic building block that combines an aldehyde and a carboxylic acid functional group on a benzene ring. This bifunctional nature makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is particularly valuable for pharmaceutical chemists and agrochemical researchers developing new active ingredients, where the fluorine atom and the two reactive sites enable precise structural modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting CNS disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Polymer & Resin Modifier: Incorporated as a monomer or cross-linking agent to create specialty polymers with enhanced thermal, chemical, or surface properties.
• Complex Ligand & Catalyst Development: Utilized in organometallic chemistry to create sophisticated chelating ligands for catalytic systems and metal-organic frameworks (MOFs).
• Diagnostic Reagent & Probe Synthesis: Acts as a starting material for fluorescent dyes, biomarkers, and other molecular probes used in biochemical assays and medical diagnostics.

Basic Information

Item	Detail
Product Name	4-Carboxy-3-Fluorobenzaldehyde
CAS No.	604000-97-7
Molecular Formula	C8H5FO3
Molecular Weight	168.12 g/mol
Synonyms	3-Fluoro-4-formylbenzoic acid; 4-Formyl-2-fluorobenzoic acid; 2-Fluoro-4-carboxybenzaldehyde; 3-Fluoro-4-carboxybenzaldehyde; 4-Aldehydo-2-fluorobenzoic acid; 2-Fluoroterephthalaldehyde-4-carboxylic acid; 4-Carboxy-3-fluorobenzaldehyde; Benzoic acid, 4-formyl-3-fluoro-
EINECS	Contact for details

Quality Control

Our 4-Carboxy-3-Fluorobenzaldehyde is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment supports applications requiring high-purity intermediates for GMP or research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using an inert atmosphere to minimize oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.