Description

7-[2-(Cyclopropylmethoxy)-6-Hydroxyphenyl]-1,4-Dihydro-5-[(3S)-3-Piperidinyl]-2H-Pyrido[2,3-D][1,3]Oxazin-2-One Hydrochloride is a high-purity, non-racemic pharmaceutical intermediate and research chemical. This compound is of significant value for its role as a key synthetic building block in the development of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules for preclinical and clinical studies.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of advanced drug candidates, particularly in oncology and central nervous system (CNS) research.
• Protease Inhibitor Research: Serves as a core scaffold for the design and development of novel protease inhibitors, leveraging its complex heterocyclic structure.
• Kinase Inhibitor Development: Used in medicinal chemistry programs targeting specific kinase pathways due to its privileged structural motifs.
• Chemical Biology & Probe Synthesis: Employed in the creation of chemical probes for studying enzyme function and signal transduction pathways in biological systems.
• Process Chemistry & Scale-Up: Supplied to CROs and CDMOs for process development, optimization, and the production of batches under cGMP for clinical trials.
• Reference Standard: Utilized as a high-purity analytical standard for method development, validation, and quality control in API manufacturing.

Basic Information

Item	Details
Product Name	7-[2-(Cyclopropylmethoxy)-6-Hydroxyphenyl]-1,4-Dihydro-5-[(3S)-3-Piperidinyl]-2H-Pyrido[2,3-D][1,3]Oxazin-2-One Hydrochloride
CAS No.	600734-06-3
Molecular Formula	C22H25N3O4 · HCl
Molecular Weight	439.91 g/mol
Synonyms	(3S)-5-(3-Piperidinyl)-7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-1,4-dihydro-2H-pyrido[2,3-d][1,3]oxazin-2-one hydrochloride; 5-[(3S)-3-Piperidinyl]-7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-1,4-dihydro-2H-pyrido[2,3-d][1,3]oxazin-2-one hydrochloride; UNII-7S5I7O3E1N; 7S5I7O3E1N; BDBM50102657; AKOS015915991; ZINC000003869007; CHEMBL3186662
EINECS	Contact for details

Quality Control

Our production of 7-[2-(Cyclopropylmethoxy)-6-Hydroxyphenyl]-1,4-Dihydro-5-[(3S)-3-Piperidinyl]-2H-Pyrido[2,3-D][1,3]Oxazin-2-One Hydrochloride adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) with full traceability are provided for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.